The latest research aims to improve treatment for major depression, providing faster relief and fewer side effects.
Doctors still lack a precise method for determining the most effective medication, resulting in multiple trials for individuals with depression.
Antidepressants typically take weeks or months to work, delaying the assessment of their effectiveness. Additionally, around 30% of individuals remain unsatisfied with various medication attempts, which is referred to by doctors as treatment-resistant depression.
Due to the time-consuming and unreliable nature of this trial-and-error process, depression can persist and hinder your daily life.
Over 63% of adults and 70% of teens with depression experience significant distress and disruption in their lives, according to recent data from the National Institute of Mental Health. Depression also increases the risk of suicide thoughts and attempts.
Inflammation serves as the body's inherent mechanism for protecting against infections and injuries. However, when it occurs inappropriately or becomes unregulated, it has the potential to exacerbate numerous diseases. Recent research indicates that depression is among the conditions most affected by this phenomenon.
In the largest-ever study of depression and inflammation, published in 2021 in the American Journal of Psychiatry, scientists confirmed the link between the two. They found people with depression had more inflammation than those without the mental health disorder. This was true even after scientists accounted for other factors involved in depression.
Research suggests that incorporating medications that have anti-inflammatory properties into existing antidepressant treatments may be potentially beneficial. Additionally, making lifestyle adjustments such as engaging in regular exercise and maintaining a nutritious diet has been shown to have potential in mitigating symptoms associated with depression.
The gut-brain connection is associated with the presence of a vast number of bacteria and microorganisms, commonly referred to as microbes, within the gut. These microbes can have varying effects, with some contributing positively while others exerting negative influences. Imbalances in the microbial composition have been linked to several health issues, such as depression and inflammation.
Recent research suggests that probiotics can potentially contribute to a more balanced gut microbial environment and potentially alleviate symptoms of depression. Probiotics are living bacteria that are commonly found in fermented foods, such as yogurt, or are available as supplements. It is worth noting that the use of probiotics generally entails minimal side effects.
There is a need for further scientific understanding of the mechanisms through which probiotics affect individuals with depression. Several studies indicate that the combination of probiotics with antidepressant drugs yields the most beneficial outcomes. Additionally, research suggests that distinct strains or types of probiotics may be effective in addressing specific symptoms associated with depression.
In the meantime, it may be advisable to consider trying a probiotic for a month to assess any potential improvement in your mood. However, it is important to note that any decision regarding the discontinuation of prescription medications should only be made with the approval and guidance of your doctor.